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Post-surgical recovery for patients has been a major factor driving technology in healthcare. Wound closure devices such as tapes, sutures, and staples have been considered as a gold standard for most surgical procedures to date. However, several disadvantages such as spaces between tissues, sepsis and uneven tissue closure cases slowly became causes for concerns. Sepsis requiring aspiration from spaces or pockets created due to uneven tissue closure increased infection and mortality rates, particularly for large flap surgeries. Tissue adhesives and sealants are chemical compounds similar in the function of normal adhesives but are biocompatible. Tissue adhesives are attractive alternatives to staples and sutures as they are easy to apply, require a shorter time for holding tissue, involve lesser pain and require very simple equipment for application. Due to the complete absence of pins, needles, and staples they also greatly decrease the incidence of sharps injuries faced b...
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